Johnson & Johnson: Developed the first COVID-19 vaccine approved for emergency use in the United States.
Pfizer Inc.: Developed a COVID-19 vaccine in collaboration with BioNTech, which has been widely used globally.
Roche Holding AG: Developed groundbreaking cancer drugs, including Herceptin and Avastin.
Novartis AG: Developed Gleevec, a breakthrough drug for the treatment of chronic myeloid leukemia.
Merck & Co., Inc.: Developed Keytruda, a revolutionary immunotherapy drug for cancer treatment.
Sanofi SA: Developed Lantus, an innovative insulin product for the management of diabetes.
AstraZeneca PLC: Developed innovative drugs for various therapeutic areas, including oncology and respiratory diseases.
GlaxoSmithKline PLC: Developed Advair, a widely prescribed medication for asthma and chronic obstructive pulmonary disease (COPD).
AbbVie Inc.: Developed Humira, the world's best-selling prescription drug for the treatment of autoimmune diseases.
Bristol Myers Squibb Company: Developed Opdivo, an immune checkpoint inhibitor for the treatment of cancer.
Eli Lilly and Company: Developed Prozac, a widely used antidepressant medication.
Amgen Inc.: Developed innovative biologic drugs, including Enbrel for rheumatoid arthritis and Neulasta for neutropenia.
Bayer AG: Developed various drugs and healthcare products, including Aspirin and Xarelto.
Takeda Pharmaceutical Company Limited: Developed Entyvio, a treatment for inflammatory bowel disease.
Boehringer Ingelheim GmbH: Developed Spiriva, a popular medication for chronic obstructive pulmonary disease (COPD).
Gilead Sciences, Inc.: Developed antiviral drugs for the treatment of HIV/AIDS, including Truvada and Atripla.
Novo Nordisk A/S: Developed insulin products and other treatments for diabetes.
Astellas Pharma Inc.: Developed drugs in various therapeutic areas, including organ transplantation and urology.
Teva Pharmaceutical Industries Ltd.: Developed a wide range of generic medications for various conditions.
Daiichi Sankyo Company, Limited: Developed medications for cardiovascular diseases, including hypertension and heart failure.
Otsuka Holdings Co., Ltd.: Developed Abilify, a widely used medication for schizophrenia and bipolar disorder.
Eisai Co., Ltd.: Developed Aricept, a drug for the treatment of Alzheimer's disease.
CSL Limited: Developed plasma-derived therapies for various medical conditions, including immune deficiencies and bleeding disorders.
Biogen Inc.: Developed drugs for neurological conditions, including multiple sclerosis and spinal muscular atrophy.
Regeneron Pharmaceuticals, Inc.: Developed innovative drugs, including Eylea for age-related macular degeneration.
Alexion Pharmaceuticals, Inc.: Developed Soliris, a treatment for rare diseases such as paroxysmal nocturnal hemoglobinuria (PNH).
Mylan N.V.: Developed a wide range of generic pharmaceutical products.
Shire (now part of Takeda Pharmaceutical Company Limited): Developed treatments for rare diseases, including hemophilia and hereditary angioedema.
Allergan (now part of AbbVie Inc.): Developed Botox, a popular cosmetic and therapeutic drug.
Vertex Pharmaceuticals Incorporated: Developed breakthrough drugs for cystic fibrosis, including Kalydeco and Trikafta.
Merck KGaA: Developed drugs and therapies for various therapeutic areas, including oncology and neurology.
Sun Pharmaceutical Industries Limited: Developed a broad portfolio of generic medications.
Johnson Matthey (formerly Johnson Matthey Pharmaceuticals): Developed active pharmaceutical ingredients (APIs) and drug delivery systems.
Ipsen: Developed drugs for rare diseases, endocrinology, and neurology.
Grifols: Developed plasma-derived therapies, including immunoglobulins and coagulation factors.
Jazz Pharmaceuticals plc: Developed drugs for sleep disorders, oncology, and neurological conditions.
Kyowa Kirin Co., Ltd.: Developed medications for various therapeutic areas, including oncology and immunology.
Almirall, S.A.: Developed treatments for dermatological conditions, including psoriasis and atopic dermatitis.
Recordati S.p.A.: Developed drugs for cardiovascular and respiratory diseases, among other therapeutic areas.
UCB S.A.: Developed medications for neurological and immunological conditions.
Sawai Pharmaceutical Co., Ltd.: Developed generic medications and contract manufacturing services.
Indivior PLC: Developed medications for the treatment of opioid dependence.
Chr. Hansen Holding A/S: Developed natural ingredient solutions for the pharmaceutical, food, and agricultural industries.
Chugai Pharmaceutical Co., Ltd.: Developed drugs for oncology, rheumatoid arthritis, and other therapeutic areas.
Seqirus (part of CSL Limited): Developed vaccines for influenza and other infectious diseases.
Aspen Pharmacare Holdings Limited: Developed a diverse range of generic and specialty pharmaceutical products.
Piramal Enterprises Limited: Developed a wide range of healthcare products and services.
Kyorin Holdings, Inc.: Developed medications for respiratory diseases and allergies.
Mitsubishi Tanabe Pharma Corporation: Developed drugs for various therapeutic areas, including neurological disorders and autoimmune diseases.
Lupin Limited: Developed a broad portfolio of generic medications.
Please note that achievements and rankings may have changed since my knowledge cutoff in September 2021, and it's always a good idea to refer to the latest information available for the most up-to-date data.